The goal and scope of the research

Monitoring of the health status of the exposed population offspring on the basis of population genetic, genealogical, genetically-epidemiological, twin and other methods of research, in accordance with the findings of clinical-genetic and laboratory examination of the exposed population offspring and in utero exposed persons.

Objectives:

  • assessment of the impact of radiation and factors accompanying radiation exposure on the health status of the offspring of the population exposed in the Southern Urals and also of in utero exposed individuals
  • organization and performance of monitoring of the health status of the exposed population offspring and in utero exposed persons
  • organization and performance of medical-genetic consultations of the population residing on the radioactively contaminated territories including those who were in utero exposed and 1st, 2nd and subsequent generations offspring of the population exposed in the Southern Urals
  • identification of the population groups who have increased risk of the development of hereditary and chromosome diseases, genetic predisposition to diseases, and of teratogenic syndromes
  • development of methods of diagnostics, monitoring, and prophylaxis of potential medical-genetic effects of population radiation exposure
  • creation of databases and registries on certain forms of hereditary pathology and diseases with genetic predisposition
  • development, scientific grounding and implementation of actions aimed at prevention of hereditary diseases in the region
  • scientific research and development of guidelines for the expert councils and public health authorities on criteria of establishing causal relationship between hereditary diseases and radiation exposure
  • study of the mechanisms and consequences of combined effect of radiation exposure to genetic patterns of parents and in utero and postnatal exposure of the offspring
  • study of the mechanisms and consequences of combined effect of radiation and non-radiation factors. Formation of the groups of population with increased genetic risk, and groups of individuals resistant to the effect of ionizing radiation

Staff

  • Sergey Shalaginov – acting head of the Laboratory, PhD in Medical Sciences
  • Anna Timkova – junior researcher
  • Ivan Gulin – geneticist
  • Marina Zub – cytogeneticist
  • Nina Doroshko – senior laboratory technician